Roger Rubio Sanchez

Dr Roger Rubio Sánchez

BSc MRes PhD

Roger is a BBSRC Discovery Research Fellow hosted at the Department of Chemical Engineering and Biotechnology and a Junior Research Fellow at Wolfson College. Roger's work focuses on exploiting the tools of DNA nanotechnology to elucidate new biophysical principles for membrane signalling and bio-engineering cell-like agents for healthcare and biomedicine.

Roger Rubio Sanchez

Roger completed his BSc in Biotechnology Engineering at the Instituto Tecnológico y de Estudios Superiores de Monterrey in Mexico City (2015). He moved to Cambridge UK in 2017 to read for an MRes in Nanoscience and Nanotechnology as part of the Centre for Doctoral Training NanoDTC programme, through which he then obtained a PhD in Physics from the Cavendish Laboratory (2021). He continued his research through two postdoctoral appointments, first at Imperial College London (Department of Chemistry) and later back at the University of Cambridge (Department of Chemical Engineering and Biotechnology).

Roger's work has involved studying the biophysical principles that govern the spatial and temporal organisation of membranes, with the goal of constructing DNA nanostructures that could mimic the form and function of cell-surface machinery. By applying his membrane-active DNA nano-devices, Roger engineers advanced functionalities in synthetic cell-like objects, which are useful as models for fundamental research and hold great potential as next-generation biomedical platforms.

Since 2023, he has been an independent Research Fellow (BBSRC Discovery Fellow) hosted at the Department of Chemical Engineering and Biotechnology, University of Cambridge. Roger is also the coordinator and lecturer of the Bionanotechnology course, taught as part of the MRes in Nanoscience and Nanotechnology and MPhil in Micro and Nanotechnology Enterprise programmes.

Roger’s research interests follow the exciting goals, applications, and impact of synthetic cell science and engineering biology. Roger applies his expertise to advance the toolkit available to engineer synthetic cells and unlock their promised applications to biomedicine.

By applying the tools of amphiphilic DNA nanotechnology to lipid membranes and their phase behaviour, Roger´s work leads to the construction of synthetic cells with purposefully designed functionality. His bespoke DNA nanostructures can impart function to synthetic-cell lipid membranes so that these cell-like objects exhibit behaviours typically observed in living organisms, which can in turn allow synthetic cells to detect and respond to changes in their surroundings.

Exploiting these tailored and bio-mimetic DNA-membrane platforms, Roger designs synthetic cells with the ability to coordinate responses similar to immune cells. With his approach to constructing immune-like synthetic cells, Roger plans to unlock new pathways to detect and respond to the presence of pathogens, enabling the application of synthetic-cell biotechnologies for bottom-up immunity in healthcare and bio-medicine.

What's on

A close-up of a purple allium flower with a spherical cluster of tiny blossoms on a tall stem, set against a softly blurred garden background.

Wolfson Bulb Trail

18/04/2026 at 10.00

Our new bulb trail allows you to enjoy our thoughtfully planted displays and explore our beautiful College Gardens at your own pace.

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Art Exhibition: 'Epic Journeys'

18/04/2026 at 10.00

Visit Wolfson's latest exhibition 'Epic Journeys' featuring work by distinguished artist Hassan Aliyu.

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Lessons from WHO Non-Communicable Disease Initiative about Chronic Disease

21/04/2026 at 17.30

What links osteoporosis and heart disease? Dr Gordon Klein reveals surprising connections between two of ageing's biggest health challenges, and what they mean for prevention.

A pair of red, white, and blue patterned knitted gloves in progress with knitting needles and yarn rest on top of two books, one featuring a colorful bird and floral illustration on the cover.

Making the Past: Historical Recreation and Material Culture

29/04/2026 at 13.00

How do recreations of clothes, food, and objects generate new questions and knowledge about historical practices and lived experience?

Smiling woman with short gray hair and glasses stands in front of library bookshelves while holding up the book “Chain Reaction: The Wondrous Chemistry of Everyday Life” by Ijeoma Uchegbu.

Professor Dame Ijeoma Uchegbu: Chain Reaction

29/04/2026 at 17.30

Join Wolfson's President, Professor Dame Ijeoma Uchegbu, for the launch of her new book, Chain Reaction.

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