Giles Yeo

Professor Giles Yeo


Giles is a geneticist interested in studying the brain's control of food intake and body weight, and how these might be dysregulated in obesity.

Giles Yeo

Giles Yeo is from San Francisco, receiving his bachelor’s degree in Molecular and Cell Biology from the University of California, Berkeley. In 1994, he came to Cambridge joining the lab of Professor Sydney Brenner (Nobel Laureate 2002) for his PhD studies. In 1998 he began his postdoctoral training with Professor Sir Stephen O’Rahilly in the Department of Clinical Biochemistry, working on the genetics of severe human obesity.

Giles was the first to report that mutations in the melanocortin-4 receptor (MC4R) and in the neurotrophic receptor TRKB resulted in severe human obesity. In 2007, Giles became Scientific Director of the core Genomics/Transcriptomics facilities and a group leader at the University of Cambridge Metabolic Research Labs. Giles is a postgraduate Tutor and Fellow of Wolfson College. He is also the current President of the British Society for Neuroendocrinology.

Recognitions & achievements

  • President, British Society for Neuroendocrinology

Research interests

Giles’s group is interested in studying the brain control of food intake and body weight, and how these might be dysregulated in obesity. Giles also presents science documentaries for the BBC. His critically acclaimed investigative piece Clean eating – the dirty truth, also for BBC Horizon, was screened on 19 January 2017 and prompted an important national debate about dieting advice and evidence based science. He is also one of the presenters on BBC’s Trust Me I’m a Doctor. His first book, Gene Eating: the science of obesity and truth about diets was released in December 2018. His latest book, Why Calories Don't Count, is out now.