Simon is Professor of General Practice and also an a member of the MRC Epidemiology Unit where he leads the Prevention of Diabetes and other metabolic disorders Programme. The programme contributes to efforts aimed at preventing the growing burden of non-communicable disease including obesity, diabetes, cardiovascular disease and cancer, by translating epidemiological knowledge into preventive action, and evaluating the effectiveness of a range of preventive approaches in randomised trials. He published the first diabetes risk score and the first trial of screening for type 2 diabetes. He has completed over 30 trials and authored over 300 publications.
Simon is also a GP at Lensfield Medical Practice in Cambridge, and an Honorary Consultant at Addenbrooke's Hospital.
The National Academy of Medical Sciences is an independent body whose mission is to advance biomedical and health research and its translation into benefits for society. Fellows are elected "for their outstanding contributions to biomedical and health science, leading research discoveries, and translating developments into benefits for patients and the wider society."